Toll-like receptors and myocardial contractile dysfunction

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Toll-like receptors and myocardial contractile dysfunction.

Toll-like receptors (TLRs), vertebrate homologues of the drosophila Toll receptor, have been shown to play essential roles in the innate immune response. As TLRs recognize pathogen-associated molecular patterns (PAMPs), they are also known as pattern recognition receptors (PRRs). So far, 11 members of human TLRs have been identified. Roles of TLRs have been vigorously studied also in the area o...

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Toll-Like Receptors and Myocardial Inflammation

Toll-like receptors (TLRs) are a member of the innate immune system. TLRs detect invading pathogens through the pathogen-associated molecular patterns (PAMPs) recognition and play an essential role in the host defense. TLRs can also sense a large number of endogenous molecules with the damage-associated molecular patterns (DAMPs) that are produced under various injurious conditions. Animal stud...

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I-23: Reproduction and Toll Like Receptors(TLRs

Female and male reproductive tracts are of interest sites to study of immune system because they encounter specific infections such as those are sexually transmitted. Furthermore, female reproductive tract is in close contact with allogenic sperms and transmitted microorganisms during intercourse and semi allogenic fetus during pregnancy. In mammals, there are two types of immune responses, the...

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Increased Expression of Toll-Like Receptors 2 and 4 in Renal Transplant Recipients that Develop Allograft Dysfunction: A Cohort Study

Background: The incidence of ischemic reperfusion injury (IRI) in early phase post-transplantation and activation of toll-like receptor (TLR-2) and TLR-4 remarkably impact the outcome of a renal allograft. Objective: To investigate whether the expression of TLRs in peripheral blood mononuclear cells (PBMCs) can predict the clinical outcome of kidney allografts. Methods: We obtained blood sample...

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ژورنال

عنوان ژورنال: Cardiovascular Research

سال: 2008

ISSN: 0008-6363

DOI: 10.1093/cvr/cvn044